Running back Saquon Barkley gains 53 yards on back-to-back carries in fourth quarter.

Check out the top plays from the Giants' Week 6 loss to the Buffalo Bills.

Head Coach Brian Daboll discusses tight road loss in Buffalo.

Quarterback Tyrod Taylor discusses key moments from the Giants matchup against the Bills on Sunday Night Football.

Running back Saquon Barkley talks to reporters following his first game back from an ankle injury that sidelined him three weeks.

Tight end Darren Waller discusses the final sequence in the Giants' Week 6 loss to the Bills on Sunday Night Football.

Running back Saquon Barkley's best runs from his 93-yard game on Sunday Night Football against the Buffalo Bills.

Madelyn Burke, Victor Cruz and Amani Toomer break down the Giants' Week 6 loss to the Buffalo Bills in Giants Postgame Live.

Offensive lineman Justin Pugh talks to the media following his first NFL game in nearly a year.

Safety Dane Belton talks to the media about the Giants' defensive performance against the Bills on Sunday Night Football.

Linebacker Bobby Okereke jars ball loose from Gabriel Davis; Micah McFadden recovers for a Giants' takeaway.

Linebacker Bobby Okereke's second tipped pass leads to a Micah McFadden interception.

Quarterback Tyrod Taylor's 30-yard rainbow ball to Darius Slayton moves the chains.

Quarterback Tyrod Taylor finds tight end Darren Waller for a 20-yard gain.

Wide Receiver Darius Slayton comes away with a 27-yard reception along the sideline.

Linebacker Bobby Okereke diving pass break-up forces Bills 3rd down.

Kicker Graham Gano's 29-yard field goal helps Giants regain lead in the fourth quarter.

Kicker Graham Gano hits 29-yard field goal.

Coach Brian Daboll joins Madelyn Burke and Carl Banks to preview Week 6 vs. Buffalo Bills.

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