Eli Manning, the reigning NFC Offensive Player of the Week, picked up where he left off and fired 10-straight completions to open "Monday Night Football" against the Eagles, including a 13-yard touchdown to Odell Beckham Jr. on the first drive of the primetime matchup.

After being shut out in Philadelphia a year ago, the Giants were on the board less than five minutes into the game and hunting for more at Lincoln Financial Field.

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With 120 net yards already under their belt and the defense forcing a three-and-out on the Eagles' first possession, the Giants were approaching the red zone again when Manning seemingly upped his total to 11 consecutive completions on a short pass to tight end Larry Donnell. But linebacker DeMeco Ryans wrestled the ball away from Donnell for what technically went down as an interception.

That's when it all started to go wrong.

A roughing the passer penalty kept the Eagles' ensuing drive alive and ultimately led to a touchdown. From there, the Giants turned the ball over on downs, threw a pick-six on the next drive, fumbled on the one after that, and punted on their next eight possessions to end the 27-7 divisional loss.  

WHAT THE LOSS MEANS FOR THE GIANTS

The good news is the Giants won't have to travel back to Philadelphia, where they have been outscored 54-7 in the last two trips. The bad news is the Giants are just 3-12 against the Eagles in their last 15 meetings. Nonetheless, here they are in the thick of the NFC East, tied atop the standings with the Eagles at 3-3 on the season. Dallas, the Giants' next opponent, is just behind at 2-3 after its bye week, and Washington dropped to 2-4 with a loss to the Jets.

**>> EXPERTS REACT TO MNF LOSS**

"I thought our first drive was as good of a drive as we've had," Giants coach Tom Coughlin said. "And that really excited me for the rest of the day, but from that point on, there wasn't a lot to get excited about. So we play again in six days. We play last year's divisional champion, and we have to get our chins up off the floor real quick."

WHAT THE WIN MEANS FOR THE EAGLES

As it was with the Giants, the sky in Philadelphia was falling after the Eagles started the season 0-2. But, again like the Giants, they fought back and made themselves relevant again by winning three of their last four games to set up a Sunday night matchup against the undefeated Panthers.   

"Our motto from, I think, Week 3 has just been take it one game at a time," quarterback Sam Bradford said. "And that is kind of what we have done. We've won our last two at home, we've won three of our last four and that's really how we are handling the rest of the season. Next week, we have a big one against Carolina and that is really all that we are concerned with right now."