With middle linebacker Dan Connor being placed on injured reserve and running back Brandon Jacobs signing with the team, there have been changes to the Giants depth chart in Week 2.
Here is the breakdown heading into Sunday's contest against the Denver Broncos:
| OFFENSE | ||||
| First | Second | Third | Other | |
| WR | Hakeem Nicks | Rueben Randle | ||
| LT | Will Beatty | |||
| LG | Kevin Boothe | James Brewer | ||
| C | David Baas | Jim Cordle | ||
| RG | Chris Snee | Brandon Mosley | ||
| RT | Justin Pugh | David Diehl | ||
| TE | Brandon Myers | Bear Pascoe | Larry Donnell | Adrien Robinson |
| WR | Victor Cruz | Louis Murphy | Jerrel Jernigan | |
| QB | Eli Manning | Curtis Painter | Ryan Nassib | |
| FB | Henry Hynoski | Bear Pascoe | ||
| RB | David Wilson | Da'Rel Scott | Michael Cox | Brandon Jacobs, Andre Brown |
| DEFENSE | ||||
| First | Second | Third | Other | |
| LDE | Justin Tuck | Damontre Moore | Justin Trattou | |
| LDT | Linval Joseph | Shaun Rogers | Johnathan Hankins | |
| RDT | Cullen Jenkins | Mike Patterson | ||
| RDE | Mathias Kiwanuka | Jason Pierre-Paul | ||
| SLB | Keith Rivers | |||
| MLB | Mark Herzlich | Allen Bradford | ||
| WLB | Spencer Paysinger | Jacquian Williams | ||
| LCB | Corey Webster | Jayron Hosley | Terrell Thomas | |
| RCB | Prince Amukamara | Aaron Ross | Trumaine McBride | |
| FS | Ryan Mundy | |||
| SS | Antrel Rolle | Cooper Taylor | ||
| SPECIAL | ||||
| First | Second | Third | Other | |
| P | Steve Weatherford | |||
| PK | Josh Brown | |||
| H | Steve Weatherford | |||
| LS | Zak DeOssie | |||
| KR | Michael Cox | David Wilson | Jerrel Jernigan | Da'Rel Scott |
| PR | Rueben Randle | Jayron Hosley | Jerrel Jernigan | David Wilson |
