AT A GLANCE

No historic comeback this time. The Giants, now outscored 63-6 in three first halves this season, were unable to climb out of another hole on Thursday Night Football and fell 30-12 to the undefeated San Francisco 49ers.

UP NEXT

After playing twice on the road in a five-day span, the Giants have 11 days until their next game. They will host the Seattle Seahawks on Monday Night Football in their third primetime outing in the first four weeks of the season.

WHAT WE LEARNED ABOUT THE OFFENSE

🏈 The Giants had ruled out four players due to injuries heading into Thursday night, and three of them were on offense: running back Saquon Barkley (ankle), left tackle Andrew Thomas (hamstring), and interior offensive lineman Ben Bredeson (concussion). Barkley was hurt with 1:02 remaining in the Giants' dramatic 31-28 victory against the Cardinals. His lower leg bent awkwardly at the end of a two-yard run on the team's final offensive possession. Bredeson also suffered a concussion during the game and remains in the protocol.

🏈 With Thomas and Bredeson out, the Giants rolled out their third different offensive line in three games. From left to right, the starters were Joshua Ezeudu, Shane Lemieux, rookie John Michael Schmitz, Marcus McKethan, and Evan Neal. Only Schmitz and Neal started in Week 1.

🏈 Wide receiver Wan'Dale Robinson made his 2023 debut and caught four passes for 21 yards. His rookie season ended when he tore his ACL against Detroit last Nov. 20, a game in which the second-round pick had nine catches for 100 yards. He had previously injured his knee in the season-opening victory in Tennessee and missed the next four games.

🏈 The Giants managed just 88 yards and converted three of seven first downs in the first half, playing into the hands of the 49ers, who won the time of possession 20:00-10:00. The chasm grew from there. Overall, they were outgained 441-150 in total yards, 141-29 in rushing yards, and 39:10 to 20:50 in time of possession.

🏈 The Giants have been outscored 63-6 in three first halves this season: 26-0 vs. Cowboys, 20-0 vs. Cardinals, and 17-6 vs. 49ers.

🏈 Matt Breida, who spent his first three seasons in San Francisco, started in place of Barkley. The veteran found the end zone on an eight-yard run up the middle to bring the Giants within five points early in the second half. They didn't score again as the 49ers closed with 13 unanswered points.

🏈 After sparking the Giants with 89 yards on just two catches in Week 2, rookie wide receiver Jalin Hyatt did not have a target on Thursday.

WHAT WE LEARNED ABOUT THE DEFENSE

🏈 Outside linebacker Azeez Ojulari missed his second consecutive game due to a hamstring injury.

🏈 The Giants were the first team since the 2007 Jets not to have a takeaway or sack through two games in a season after making the playoffs. Outside linebacker Kayvon Thibodeaux changed that with a sack of Brock Purdy on the opening drive of Thursday's game. Defensive linemen Leonard Williams and D.J. Davidson combined for the Giants' second sack.

🏈 Inside linebacker Micah McFadden had one of the most active games of his young career, racking up a personal-best four tackles for loss on the night. The second-year pro led the team with 11 tackles.

🏈 The Giants struggled to get off the field as the 49ers converted seven of their 10 third downs and controlled the clock for exactly 20 minutes in the first half.

🏈 Rookie cornerback Deonte Banks suffered an arm injury in the first half. Adoree' Jackson slid back to the outside in his place while Darnay Holmes took over the slot.

WHAT WE LEARNED ABOUT SPECIAL TEAMS

🏈 After making the game-winning field goal on Sunday, Graham Gano tied a franchise record with a 57-yard field goal late in the first half. Gano made one from the same distance last season in Dallas, and Aldrick Rosas also had a 57-yarder against Chicago in 2018.

🏈 Gano now has now made 21 field goals from 50 yards or longer with the Giants. Joe Danelo is second in franchise history with nine.

IN-GAME INJURY REPORT

NYG: CB Deonte Banks (arm), DL D.J. Davidson (elbow)

INACTIVES

NYG: RB Saquon Barkley (ankle), CB Cor'Dale Flott, S Gervarrius Owens, OLB Azeez Ojulari (hamstring), OL Ben Bredeson (concussion), T Andrew Thomas (hamstring), DL Jordon Riley

SF: G Nick Zakelj, RB Tyrion Davis-Price, DT Kalia Davis, ILB Jalen Graham, WR Brandon Aiyuk (shoulder), CB Ambry Thomas (knee), QB Brandon Allen