It will be five starting offensive line combinations in five games for the Giants when they face the Miami Dolphins Sunday in Hard Rock Stadium.

That was assured when rookie center John Michael Schmitz was declared out of the game because of the shoulder injury he suffered Monday night against Seattle. He had started each of the first four games.

In addition to Schmitz, stellar left tackle Andrew Thomas will miss his fourth consecutive game with a hamstring injury, and guard Shane Lemieux will be sidelined with a groin injury.

On Saturday, the Giants elevated offensive linemen Jaylon Thomas and Jalen Mayfield from the practice squad.

Running back Saquon Barkley, meanwhile, was listed as questionable on Friday's final injury report but was ruled out on the inactive list, which is released 90 minutes prior to kickoff. Barkley was limited in practice and has missed the last three games with an ankle sprain. Before the Seattle game he was listed as doubtful.

Below is the inactive list for Giants vs. Dolphins:

GIANTS INACTIVES

• RB Saquon Barkley
• S Gervarrius Owens
• LB Micah McFadden
• C John Michael Schmitz
• G Shane Lemieux
• T Andrew Thomas
• DL Jordon Riley

DOLPHINS INACTIVES

• CB Kelvin Joseph
• OLB Jaelan Phillips
• RB Salvon Ahmed
• WR Chase Claypool
• NT Brandon Pili
• QB Skylar Thompson